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1.

Prevention and treatment of papillomavirus-related cancers through immunization.

Frazer, Ian H; Leggatt, Graham R; Mattarollo, Stephen R.

Annu Rev Immunol ; 29: 111-38, 2011.

Article in English | MEDLINE | ID: mdl-21166538

2.

Metabolomics at the tumor microenvironment interface: Decoding cellular conversations.

Berrell, Naomi; Sadeghirad, Habib; Blick, Tony; Bidgood, Charles; Leggatt, Graham R; O'Byrne, Ken; Kulasinghe, Arutha.

Med Res Rev ; 44(3): 1121-1146, 2024 May.

Article in English | MEDLINE | ID: mdl-38146814

3.

Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment.

Kobayashi, Takumi; Lam, Pui Yeng; Jiang, Hui; Bednarska, Karolina; Gloury, Renee; Murigneux, Valentine; Tay, Joshua; Jacquelot, Nicolas; Li, Rui; Tuong, Zewen Kelvin; Leggatt, Graham R; Gandhi, Maher K; Hill, Michelle M; Belz, Gabrielle T; Ngo, Shyuan; Kallies, Axel; Mattarollo, Stephen R.

Blood ; 136(26): 3004-3017, 2020 12 24.

Article in English | MEDLINE | ID: mdl-32818230

4.

Investigating T Cell Immunity in Cancer: Achievements and Prospects.

Zeng, Zhen; Chew, Hui Yi; Cruz, Jazmina G; Leggatt, Graham R; Wells, James W.

Int J Mol Sci ; 22(6)2021 Mar 12.

Article in English | MEDLINE | ID: mdl-33809369

5.

Galectin-1 is associated with poor prognosis in patients with cutaneous head and neck cancer with perineural spread.

Chawla, Sharad; Warren, Timothy A; Wockner, Leesa F; Lambie, Duncan L J; Brown, Ian S; Martin, Thomas P C; Khanna, Rajiv; Leggatt, Graham R; Panizza, Benedict J.

Cancer Immunol Immunother ; 65(2): 213-22, 2016 Feb.

Article in English | MEDLINE | ID: mdl-26759008

6.

Control of B-cell lymphoma by therapeutic vaccination and acquisition of immune resistance is independent of direct tumour IFN-gamma signalling.

Rearden, Rory; Sah, Amelia; Doff, Brianna; Kobayashi, Takumi; McKee, Sara J; Leggatt, Graham R; Mattarollo, Stephen R.

Immunol Cell Biol ; 94(6): 554-62, 2016 07.

Article in English | MEDLINE | ID: mdl-26786233

7.

HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells.

Bergot, Anne-Sophie; Ford, Neill; Leggatt, Graham R; Wells, James W; Frazer, Ian H; Grimbaldeston, Michele A.

PLoS Pathog ; 10(10): e1004466, 2014 Oct.

Article in English | MEDLINE | ID: mdl-25340820

8.

Recent progress in vaccination against human papillomavirus-mediated cervical cancer.

McKee, Sara J; Bergot, Anne-Sophie; Leggatt, Graham R.

Rev Med Virol ; 25 Suppl 1: 54-71, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25752816

9.

Regulation of immune responses to HPV infection and during HPV-directed immunotherapy.

Bhat, Purnima; Mattarollo, Stephen R; Gosmann, Christina; Frazer, Ian H; Leggatt, Graham R.

Immunol Rev ; 239(1): 85-98, 2011 Jan.

Article in English | MEDLINE | ID: mdl-21198666

10.

A combination of local inflammation and central memory T cells potentiates immunotherapy in the skin.

Fiorenza, Salvatore; Kenna, Tony J; Comerford, Iain; McColl, Shaun; Steptoe, Raymond J; Leggatt, Graham R; Frazer, Ian H.

J Immunol ; 189(12): 5622-31, 2012 Dec 15.

Article in English | MEDLINE | ID: mdl-23144496

11.

NKT cells inhibit antigen-specific effector CD8 T cell induction to skin viral proteins.

Mattarollo, Stephen R; Yong, Michelle; Gosmann, Christina; Choyce, Allison; Chan, Dora; Leggatt, Graham R; Frazer, Ian H.

J Immunol ; 187(4): 1601-8, 2011 Aug 15.

Article in English | MEDLINE | ID: mdl-21742969

12.

Histone deacetylase inhibitors in the generation of the anti-tumour immune response.

Leggatt, Graham R; Gabrielli, Brian.

Immunol Cell Biol ; 90(1): 33-8, 2012 Jan.

Article in English | MEDLINE | ID: mdl-22064708

13.

Invariant NKT cells in hyperplastic skin induce a local immune suppressive environment by IFN-gamma production.

Mattarollo, Stephen R; Rahimpour, Azad; Choyce, Allison; Godfrey, Dale I; Leggatt, Graham R; Frazer, Ian H.

J Immunol ; 184(3): 1242-50, 2010 Feb 01.

Article in English | MEDLINE | ID: mdl-20028654

14.

Secretion of IFN-gamma but not IL-17 by CD1d-restricted NKT cells enhances rejection of skin grafts expressing epithelial cell-derived antigen.

Mattarollo, Stephen R; Yong, Michelle; Tan, Lieven; Frazer, Ian H; Leggatt, Graham R.

J Immunol ; 184(10): 5663-9, 2010 May 15.

Article in English | MEDLINE | ID: mdl-20410490

15.

Both treated and untreated tumors are eliminated by short hairpin RNA-based induction of target-specific immune responses.

Gu, Wenyi; Cochrane, Melanie; Leggatt, Graham R; Payne, Elizabeth; Choyce, Allison; Zhou, Fang; Tindle, Robert; McMillan, Nigel A J.

Proc Natl Acad Sci U S A ; 106(20): 8314-9, 2009 May 19.

Article in English | MEDLINE | ID: mdl-19416823

16.

IFN-gamma promotes generation of IL-10 secreting CD4+ T cells that suppress generation of CD8 responses in an antigen-experienced host.

Liu, Xiao Song; Leerberg, Joanne; MacDonald, Kelli; Leggatt, Graham R; Frazer, Ian H.

J Immunol ; 183(1): 51-8, 2009 Jul 01.

Article in English | MEDLINE | ID: mdl-19535638

17.

PD-1 and beyond to Activate T Cells in Cutaneous Squamous Cell Cancers: The Case for 4-1BB and VISTA Antibodies in Combination Therapy.

Wright, Quentin; Gonzalez Cruz, Jazmina L; Wells, James W; Leggatt, Graham R.

Cancers (Basel) ; 13(13)2021 Jul 01.

Article in English | MEDLINE | ID: mdl-34282763

18.

Regulatory T Cells but Not IL-10 Impair Cell-Mediated Immunity in Human Papillomavirus E7+ Hyperplastic Epithelium.

Bashaw, Abate Assefa; Zhou, Chenhao; Yu, Meihua; Tolley, Lynn; Leggatt, Graham R; Frazer, Ian H; Chandra, Janin.

J Invest Dermatol ; 141(5): 1264-1273.e3, 2021 05.

Article in English | MEDLINE | ID: mdl-33129828

19.

Epithelial expression of human papillomavirus type 16 E7 protein results in peripheral CD8 T-cell suppression mediated by CD4+CD25+ T cells.

Narayan, Sharmal; Choyce, Allison; Linedale, Richard; Saunders, Nicholas A; Dahler, Alison; Chan, Emily; Fernando, Germain J; Frazer, Ian H; Leggatt, Graham R.

Eur J Immunol ; 39(2): 481-90, 2009 Feb.

Article in English | MEDLINE | ID: mdl-19180468

20.

HPV vaccines: the beginning of the end for cervical cancer.

Leggatt, Graham R; Frazer, Ian H.

Curr Opin Immunol ; 19(2): 232-8, 2007 Apr.

Article in English | MEDLINE | ID: mdl-17293100

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